As someone roleplaying homeless for a while now, I go into South Los Santos on occasion. It's generally quite deserted when I go around there and Grove Street, Covenant Avenue, and Jamestown Street are a big no-go for me. The roleplay quality is just too poor for me to have any interest in going there. Civilians have no business there either as you'll be met with aggression for no apparent reason, and if you're unlucky you'll get robbed too. These are my experiences however but I do reckon it is a proper representation of these areas. And as the rest of these areas are generally deserted, except for Jamestown, there is no real reason to go there for any civilian. If the roleplay was up to standard, I would go there more often, but I doubt it will be. Roleplayers with the capability to actually roleplay generally avoid poor areas if they can.