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Midsummer Night's Dream

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    Juno Midsomer

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  1. Midsummer Night's Dream

    lmao His char invested his blood and sweat into two casinos, fraught with risks, and came out on top And his char doing a good job of hiding his quirky Vicodin addiction : P
  2. Midsummer Night's Dream

    i’m sorry but i don’t know Just kidding! I think he made an interesting guide about the niceties of roleplaying money-laundering. Well done👏
  3. Midsummer Night's Dream

    There hasn’t been any recent literature — that I’m aware of — looking into the novel Coronavirus causing the current pandemic, but there is on non-SARS coronaviruses, such as this chapter on Coronviruses from the textbook Goldman-Cecil’s Medicine. Non-SARS coronaviruses include: MERS (which causes disease in humans, and jumped to humans from Egyptian cave bats with camels as the intermediary — so a bat-to-camel-to-human route), equine coronavirus (only causes disease in horses, as the name “equine” suggests), bovine coronavirus (causes disease is cattle), canine coronavirus (dogs), and feline coronavirus (cats), among others. That chapter discusses how these non-SARS coronaviruses are error-prone; and, for this reason, the antibodies developed for them do not confer highly protective immunity — highly protective, for example, would be immunity that lasts a lifetime. Errors during viral replication are what are needed to cause antigenic drift and shift. The fact that those non-SARS coronaviruses are error-prone suggests they are capable of drift/shift, and so the immunity which antibodies confer does not last very long. But, while other non-SARS coronaviruses are error-prone RNA viruses and so have high mutability, this is not evidence that the current novel Coronavirus will be capable of antigenic drift and shift. Of course the possibility is there, especially because other non-SARS viruses in the same family are error-prone. But the presumption should be that surviving an infection and developing antibodies will confer protective immunity until, of course, it is shown otherwise; and it has not yet been shown otherwise. The presumption should not be that there is no immunity or that a virus which has just jumped to humans will frequently undergo drift/shift. (I can try looking for more sources, but I don’t have the time right now) In any case, people should not conflate antigenic drift/shift with virulence — or deadliness. A virus which is error-prone and undergoes drift or shift does not make it a deadly virus which causes serious acute conditions and quick death. It must be remembered that all viruses need the host to remain alive in order to replicate — a deceased host is useless to any virus — so strains that are deadly will probably be “deselected” (recall natural selection from the theory of evolution) in favour of less virulent virus strains. My understanding is that the influenza viruses undergo antigenic drift and shift because we allow them to by allowing them to spread and infect hosts in the population. A virus needs to have a host to replicate, and needs to replicate to undergo antigenic drift or shift (drift/shift are caused by errors or "mutations" during replication). It is impossible for a virus to replicate outside of a host — much like defying the laws of physics. So, hypothetically speaking, if everyone were hyper-aware, took infection control and personal hygiene seriously, did not mingle with wildlife or were completely isolated from wildlife and from each other, there would be very little influenza virus spread and so no shift or drift. But we’ve allowed it to become a part of the human condition by being indifferent or complacent (an e.g. of indifference that’s become ingrained is found in the common phrase “it’s just the flu”). If we treat this novel Coronavirus the same way, it too may become part of the human condition.
  4. Midsummer Night's Dream

    Cracked is right. What Taylor talking about is called antigenic drift and the similar antigenic shift. But it’s too early to say whether this virus is capable of antigenic shift or drift like the influenza viruses. So Cracked is right in saying that once you contract the virus, and your immune system develops antibodies, those antibodies will give you immunity. Whether or not the virus will undergo drift to negate this immunity remains to be seen. Of course, as someone else alluded to, there was the one case reported in China where a patient did contract it again. This is not conclusive because — as with most things — there will be outliers. That one case out of China was very likely an outlier.
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  6. Midsummer Night's Dream

    Agreed. The thread is just reminding us to ensure consistency in how we portray our characters. That’s to say, if we’ve been portraying an informed, law-abiding character who keeps abreast of world and national affairs because that character generally cares about what's happening around him or her, then a pandemic — one whose reach includes the country in which your character lives, and one over which several U.S. states have declared a state of emergency — should cause your character to feel some concern and you should be portraying that in a way that’s compatible with how you’ve been portraying your character’s nature. But if, on the other hand, it is not in your character’s nature to care (and you’ve been consistently portraying your character that way) then your character is free to show indifference without running into questionable portrayal. Essentially, just because staff have announced that a local outbreak will not be officially sanctioned does not mean characters who have consistently cared for world or national affairs can suddenly ignore this pandemic. While their decision does mean the incidence of COVID-19 here will stay at zero, it is not a licence for everyone to portray their character being indifferent. In short, just make sure your reaction is compatible with how you’ve been portraying your character.
  7. Midsummer Night's Dream

    Username: ACuriousObserver Comment: While this has some informative parts, it also contains — and I characterize it this way with all due respect to Dr. Shaw — a few inaccuracies. 1. At the bottom of the article, the process which this article calls a mutation is called antigenic drift. And it’s most common in influenza viruses — not almost all viruses known to science. While antigenic drift does occur during viral replication inside an infected host, I would be careful calling it a mutation when the intended audience is the public. The public’s conception of “mutation” typically evokes associations with science fiction — they tend to envisage a virus rapidly acquiring devestating characteristics (as seen in the 1994 bestseller The Hot Zone — and its corresponding 2019 miniseries by the same name, as well as the 1995 film Outbreak — where an Ebola-like virus in Chimpanzees rapidly became airborne); the term “mutation” evokes images of Marvel figures acquiring supernatural abilities from dramatized mutations. The reality is markedly different. For many folks, I think a gentle reminder that changes to virus genetics in the virus’ population is quite undramatic and boring might be in order. While a virus can become more virulent (cause more serious disease / poorer prognosis) or more infectious (transmit easily between hosts), or jump between host species (e.g. pangolins to humans), these changes can be self-limiting and are always affected by the niceties of nature selection, which Hollywood depictions of outbreaks tend to gloss over. Antigenic drift is even a less dramatic than what’s depicted by Hollywood cinema. All it involves is changing the antigen markers on the surface (or ”viral protein envelope,” for microbiology lingo) of the virus. What this ultimately does is disguise the virus from the host’s immune system — it can be likened to a robber putting on a disguise to become unrecognizable when they enter the same bank to rob it again. In the first instance of the virus’ exposure to a host’s immune system, during the immune response, markers known as antibodies are developed to match the antigens on the surface of the virus. That way, next time the the virus invades a host, its immune system immediately recognizes it as a foreign pathogen and B Cells (a type of lymphocyte, and part of the immune response) can release antibodies to attack the antigens on the virus. But when a virus such as one of the influenza viruses undergoes antigenic drift (changes its antigens), the host’s antibodies no longer match the new antigens — it can be said that the influenza has disguised itself. Influenza viruses often disguise themselves through antigenic drift, which explains why new vaccines have to be developed every year. But it is wrong to say that SARS-CoV-2 or novel Coronavirus 2019 is capable of antigenic drift and, as a consequence, avoid any vaccine developed for it — it’s quite possible that a vaccine will, eventually, eradicate it. It’s too soon to say that novel Coronavirus 2019 is as elusive as influenza viruses. SARS did not have a vaccine because the 2003 epidemic ended before the vaccines being developed at the time could reach clinical trials; it is not because SARS virus “overcame” any vaccine with antigenic drift and that this change spread in the SARS population. It simply became obsolete and so the vaccines were never brought to clinical trials. 2. The advice in the fourth answer is a bit worrisome. Fourteen days used to be regarded as the average incubation period (a study at John Hopkins University estimates an incubation period average of as low as 5.1 days; but it can be as low as two days). This is the period during which one is generally contagious and is asymptomatic (not displaying any symptoms). It is unclear if every asymptomatic person can transmit the virus, but they generally can. And even after developing symptoms at 14 days, one can still be contagious and release aerosol droplets when they cough. The takeaway is 14 days is the minimum — one should self-isolate, and otherwise show basic courtesy (eg. coughing into a tissue and disposing it properly) to avoid spreading it. Good hygienic practice is always helpful, but one study out of Singapore suggested that regular cleaning of surfaces, especially surfaces which which people frequently come into contact, is also necessary. That study found those who were carriers would shedded it everywhere — on surfaces too, not just through aerosol droplets. P 3. I am skeptical of the first para. where it says “the first instance of transmission [...] was from a deceased bat to a human.” I am curious to see the source here. While two Chinese studies (here and here) suggested a bat origin, there is a theory that, for 2019-nCoV, there is an intermediate host, and that pangolins are that host. In other words, the jump was from pangolins to humans, at least that’s how the theory goes. A lot of the recent studies — if not all — are inconclusive. (Some are published without being peer-reviewed because of the overwhelming number of submissions journals receive). It should be recalled that both SARS and MERS (another virus in the same family) had non-bat intermediate hosts; for SARS, recent evidence pointed to civets (a cat-like mammal) and for MERS, camels. Like SARS and MERS, I don’t think COVID-19 came directly from bats; the pangolin theory might turn out to be correct. For those who are concerned, basic hygienic practice is all that’s necessary on your part (especially if you live with someone whose medication or condition suppresses their immune system, or if they have other underlying conditions). Don’t be indifferent or complacent, but there’s also no reason to be panicking — the virus will not undergo a Hulk-like transformation.
  8. Midsummer Night's Dream

    I played Canada and led an amphibious invasion of Spain (which had fallen to the fascists after its civil war) through the Bay of Biscay on the northwest coast and Gibraltar on the southern coast, at the same time. The northern invasion quickly pushed for and took Madrid before joining with the southern front, after which they headed to the Spanish-French border and held there to prepare for France’s liberation. I had at least a dozen allied countries involved in both invasions. While preparing for the liberation of France, I joined American and British forces in their invasion of Sicily (made possible because we controlled Gibraltar). They eventually advanced through Italy — with help from Australia, NZ, South Africa, the British Raj (India), Republic of Ireland (Ireland), France, Greece, Romania, Czechoslovakia, Poland, the USSR, Republic of China (Taiwan), Iceland, Norway, Sweden and Denmark — from the south and, not long after, Italy capitulated. When those forces made it to the Italian-French border, Switzerland joined the allies — needless to say, I had historical IA turned off! — and then the liberation of France began with two simultaneous invasions from the Spanish-French border and Italian-French border. France was soon liberated; followed by Belgium and Holland; and then Germany was surrounded with USSR on the eastern side and everyone else on the Western side. It may have been many years ago, but what a memorable game it was. (I also invaded fascist Venezuela as Canada. Please don’t PLM me for poor portrayal! 😝)
  9. Midsummer Night's Dream

    OOC advantage is a problem, I agree. To be entirely honest, I was on fence about this because I’m concerned about the potential for abuse (I know many things can be abused, but that fact should not mean we overlook the potential here or in any other suggestion) As I told another:
  10. Midsummer Night's Dream

    I’m sorry, but I can’t support this. I agree with you that it can be unfair on lenders, but implementing this runs the risk of making the process unfair for the borrowers. I have seen inactive borrowers who have been taken advantage of through, among other things, penalty clauses — or agreements for secured loans whose security would constitute a penalty when enforced. Penalties are generally not sanctioned by the law of contract and are unenforceable. The idea is the freedom of contract (and freedom to contract) should not be interfered with, so clauses in an agreement which penalize the borrower are unenforceable. An example here is when a lender collects late payment and interest on the loan (the late fee typically amounts to an unenforceable penalty). If this suggestion were implemented, we might see lenders who take advantage of an inexpert or unsophisticated borrower; and when that borrower goes inactive, at which time the lender undertakes to enforce in court, the borrower would incur debt (potentially serious debt) without any possibility of having their interest defended in court. We might see all sorts of penalties being imposed on inactive — and defenceless — borrowers. It’s already happened. It’s bad enough that unenforceable penalties cause them to lose all their money; setting them so far back as to put them into the negatives would add insult to injury. I think it’s best — if lenders want to avoid risk — for lenders to find a way to screen prospective borrowers. The goal is to reduce the risk and for lenders to be a bit more prudent as to whom they lend their money.
  11. Midsummer Night's Dream

    Sorry, I forgot to reply to this. I agree that flaws should be addressed mostly in-character by advocates and judges, but that isn’t what’s been happening. I would prefer not to get into it too much because it’s the subject of a report; but it might help one see, if they were to look around or even discuss issues with relevant decision-makers, that those decision-makers have too much regard for things on an out-of-character level (sometimes, things that aren’t necessarily applicable) I’ve tried and not only was my experience different, but there was not a follow up. It’s as plain as that. I admit it was a lapse of judgment on my part to use an on-going case to respond to Copacetic’s counter narrative. I picked out the first one I looked into without intending to give anyone information that would be useful IC. I think I’ll leave it there. The discussion got tiresome when it was taken personal by another poster earlier.
  12. Midsummer Night's Dream

    It’s already been tried and that person didn’t follow up. I’m not too sure about approachable either, especially from my own experience.
  13. Midsummer Night's Dream

    @TNG What’s the controversy over saying that the criminal docket is becoming monotonous, anyway? Is guilty plea after guilty plea, day in and day out, not repetitive? And haven’t defendants been doing that lately? (Look at how many times the words “you” and “you’re” appear in your first reply. You virtually made the subject about I was talking about myself when it originally wasn’t. That’s not taking it personal?)
  14. Midsummer Night's Dream

    If you had actually read my post carefully, you’d see I started from a hypothetical perspective to illustrate the issues with monotonous counselling. I didn’t actually say our public defenders were in a trance-like state. I did not say our criminal court is monotonous. In fact, I used the word “becoming,” and expressly said it was “on the cusp of becoming [so].” I am typically very particular with my words; please don’t distort them.
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